Two of our newest papers have been published as part of the Photoswitching Proteins series and are available to read now!
The first paper, with our recent PhD graduate Steffi as first author, describes the design and application of light-regulated receptor tyrosine kinases and how the reengineering of these receptors can be used to generate signals with high spatial and temporal precision.
The second paper, in collaboration with Viviana Agus from Axxam, presents prototypical cell-based drug screening assays using Channelrhodopsin2 (ChR2) to induce changes in membrane potential and test for voltage-gated ion channel blockade.
The 1st OptogeneticsAustralia Hands-on Workshop is on today!
We have a great line-up of speakers on Day 1 and Hands-on Workshops on Day 2! To find a full program and more information about OptogeneticsAustralia, have a look at the OptogeneticsAustralia website [LINK]. You can also follow along on twitter @OptogeneticsAus.
The talks on Day 1 are open to all Monash students and staff, so feel free to join us. We are looking forward to two great days packed with optogenetics!
What better way to end 2019 than with a successful thesis defense?
Just before Christmas, Steffi defended her thesis titled “Synthetic tools for optogenetic and chemogenetic inhibition of cellular signals” at IST Austria, and passed with flying colours! Congratulations!
Steffi first joined the lab in 2014 as a Master Student, and then as a PhD Student in 2016. During her time as PhD Student, she worked both at IST Austria and at ARMI/Monash University, and was so successful in getting fellowships that she accumulated more affiliations than anyone in the lab – including Harald! Both Steffi’s scientific expertise as well as her open and easy-going personality made her an important part of the lab!
Heartfelt congratulations, Steffi! We are very proud and wish you all the best for your next steps!
(and a pleasant surprise: almost all lab members from before our Australia-move came to the defense!)
The first OptogeneticsAustralia Hands-on Workshop has been announced for 13-14 February 2020, here at ARMI!
In addition to talk and poster sessions, the program also includes exciting practical workshops! For more information about the schedule or registration and abstract submission, head over to www.optogeneticsaustralia.com/meeting/.
Our most recent Review Article about light-activated GPCRs (OptoXRs), published in Current Opinion in Structural Biology, is now available!
In it, we discuss current OptoXR approaches, applications and limitations, but also how new insights gained from GPCR structures can be used for the design of next-generation OptoXRs and what opportunities lie in the use of them.